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Ruben Kuzniecky, MD is Professor of Neurology, Co-Director of the NYU Comprehensive Epilepsy Center and director of
epilepsy research at NYU. He trained in neurology, epilepsy, and EEG at the Montreal Neurologic Institute, McGill University,
Canada. He has authored over 275 journal articles, several book chapters, 3 books on a number of topics related to epilepsy,
and has received epilepsy research grants from the NIH and numerous foundations. He is Co-PI of the epilepsy phenome
genome project, the largest epilepsy genetic study of its type funded by NIH. His research interest is focus on brain imaging and
malformations of brain development and epilepsy. Dr. Kuzniecky has been recognized for his efforts by many honorary lectures
around the world.
W elcome to the latest edition of US Neurology, which features a wide range of topical articles covering numerous areas of neurology
that are of interest to the wider biomedical community. In this edition, we discuss treatment of Duchene Muscular Dystrophy (DMD),
differential diagnosis of multifocal motor neuropathy, issues of care in multiple sclerosis and other interesting topics.
We begin with a review by Dubow and Meyer of DMD, the most common and severe form of childhood onset muscular dystrophy. The use
of steroids in DMD has a long and complex history. The authors review patterns of steroid use across countries, dosing, and physicians’
attitudes. In addition, they discuss the use of deflazacort, a corticosteroid currently seeking regulatory approval in the treatment of DMD.
Multifocal motor neuropathy (MMN) is a treatable neuropathy, but misdiagnosis can lead to delays in treatment initiation that can result in
permanent disability. Beydoun presents an article on the differentiation of MMN from the more common entrapment neuropathy. Beydoun
also co-authors a case series by Pokala et al that presents three presentations of myelopathy with differing etiologies and highlights the
need for diligence in the diagnostic procedure in order to select the most appropriate treatment.
In an increasingly complex field, there is a need to standardise educational practices and assessments in neuromuscular and electrodiagnostic
medicine. In an editorial, Quan discusses attempts to standardize practices, including the Next Accreditation System.
This edition features two articles on the subject of multiple sclerosis (MS). The increased life expectancy of MS patients has resulted in
a growing population of older adults with MS. Moti et al discuss physical activity levels in this patient cohort and highlight the need for
further research on physical activity behaviour and ageing in MS. Conversely, there is a high incidence of MS in women of childbearing
age. Wesley et al explore patients’ misconceptions about the effect of MS on pregnancy and the impact of MS medications while pregnant
Vestibular migraine is a common cause of vertigo but is under-recognised. Naegel et al review the available options for acute treatment and
prophylaxis of vestibular migraine.
Finally, neurological symptoms are common complications of cancer and cancer therapies. Dietrich and Kaiser discuss the risk factors
underlying cognitive impairment in cancer patients.
US Neurology would like to take this opportunity to thank all participants in this edition, from organizations to individuals. A special thanks
goes to our Editorial Board for their continuing support and guidance. In particular, we would like to thank the expert authors, who gave their
precious time and effort to produce an insightful selection of articles. The expert discussions and the variety of topics covered ensure there
is something of interest for every reader and we hope you find this edition useful and thought-provoking. n
TO U CH MED ICA L MEDIA