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Contents Neurodegenerative Disease Autoimmune Encephalitis 31 Autoimmune Encephalitis Frank Leypoldt, 1,2 Klaus-Peter Wandinger, 3,4 Christian G Bien 5 and Josep Dalmau 1 1. Post doctoral Research Fellow, Catalan Institution for Research and Advanced Studies (ICREA), August Pi i Sunyer Biomedical Research Institute (IDIBAPS), Barcelona, Spain; 2. Junior Attending Physician, Department of Neurology, University Medical Centre Hamburg-Eppendorf, Germany; 3. Attending Physician, Institute of Clinical Chemistry; 4. Attending Physician, Department of Neurology, University Medical-Centre Schleswig-Holstein Campus Lübeck, Germany; 5. Head of Department, Epilepsy Centre Bethel, Mara-Clinic Bethel, Bielefeld, Germany; 6. ICREA Professor, August Pi i Sunyer Biomedical Research Institute (IDIBAPS), Barcelona, Spain Amyotrophic Lateral Sclerosis Amyotrophic Lateral Sclerosis – Clinical Features, Pathophysiology and Management 38 Christophe Coupé 1 and Paul H Gordon 2 1. Clinician Psychologist; 2. Visiting Neurologist and Researcher, Centre référent maladie rare SLA, Département des Maladies du Système Nerveux, Hôpital de la Pitié-Salpêtrière, Paris, France Sympathetic Hyperactivity and Sympathovagal Imbalance in Amyotrophic Lateral Sclerosis 46 Toshio Shimizu Director, Department of Neurology, Tokyo Metropolitan Neurological Hospital, Tokyo, Japan Chronic Inflammatory Demyelinating Polyneuropathy New Treatments for Chronic Inflammatory Demyelinating Polyneuropathy 51 Emily K Mathey 1 and John D Pollard 2 1. Research Fellow; 2. Emeritus Professor, Brain and Mind Research Institute, University of Sydney, Australia Biological Agents for Chronic Inflammatory Demyelinating Polyradiculoneuropathy 57 Joerg-Patrick Stübgen Professor of Clinical Neurology/Attending Neurologist, Department of Neurology and Neuroscience, Weill Cornell Medical College/New York Presbyterian Hospital, US The Role of Neuromuscular Ultrasound in the Diagnostic of the Chronic Inflammatory Demyelinating Polyneuropathy 62 Antonios Kerasnoudis Neurologist, Department of Neurology, St Josef-Hospital, Ruhr University, Germany 4 European Neurological Review