Articles

Acute Hypertension in Intracerebral Hemorrhage Pathophysiology and Management

There have been many studies showing the elevation of the blood pressure after ICH.7-10 Qureshi et al.,11 in their large cross-sectional study,...

Advances in Diagnostic and Therapeutic Ultrasound

The first clinical studies using microbubbles and ultrasound for treatment of ischaemic stroke have shown encouraging results.4 Further new...

Are All Gadolinium-based Contrast Agents Similar? The Importance of High Stability, High Relaxivity and High Concentration

Since the original conception and introduction of magnetic resonance imaging (MRI) gadolinium-based contrast agents (GBCAs) in the 1980s, many such...

Combined Positron Emission Tomography and Magnetic Resonance Imaging Scanners—Potential Neurological Applications

Answering the first question is straightforward. The complementary anatomical and functional information obtained from separately performed MRI and...

Depression in Epilepsy Mechanisms and Therapeutic Approaches

Epilepsy and Depression – A Bi-directional RelationshipAssessing the prevalence of depression from selected clinical samples of patients with...

Efficacy of Single Photon Emission Computed Tomography in Differentiating Dementia with Lewy Bodies – A Review of Neurotransmitter and Perfusion Imaging

Dementia with Lewy bodies (DLB) is a common form of dementia. The characteristic features are: progressive dementia particularly affecting attention,...

Fluorescent-guided Surgery for High-grade Glioma

Many trials have been published or are under way concerning a variety of new approaches: the selection of patients for chemotherapy based on methyl...

Functional Brain Imaging in Dementia - The Transition from SPECT to PET

Justification of Functional Brain Imaging in the Assessment of Dementia Determining the etiology of dementia has proven to be extremely difficult...

Gadovist in Multiple Sclerosis

As diagnosis using imaging relies on counting the number of demyelinating lesions in the white matter, the presence of enhancing lesions will...

Looking Beyond the Monoamine Hypothesis

Monoamines, Neuroimaging and Sub-components of the Depressive Syndrome The monoamine hypothesis of depression 5 does not only propose the crucial...

Monitoring Cerebral Blood Flow in Neurosurgical Intensive Care

In neurosurgical practice, monitoring of CBF plays an important role, as the brain depends on continuous blood supply due to its inability to store...

Nocturnal Frontal Lobe Epilepsy - An Update on Differential Diagnosis with Non-rapid Eye Movement Parasomnia

NFLE is characterised by onset during infancy or childhood with persistence in adulthood, family history of similar NFL seizures and nocturnal...

Positron Emission Tomography Imaging in Dementia

Glucose is the main energy supply for the brain. Its metabolism maintains ion gradients and glutamate turnover and is closely coupled to neuronal...

Shocking the Wandering Nerve Vagus Nerve Stimulation After a Decade of Widespread Use

VNS has become an invaluable tool in the treatment of refractory epilepsy. It is cost-effective3-6 and has been shown to reduce the number of...

Shocking the Wandering Nerve Vagus Nerve Stimulation After a Decade of Widespread Use

Proposed Mechanisms of Vagus Nerve StimulationThe mechanism by which VNS exerts its effect has not been fully elucidated.However, several studies...

State-of-the-art Therapeutic Strategies in Parkinson's Disease

The cause of the disease is still unknown, but growing evidence suggests that it may be due to a combination of environmental and genetic factors....

The Alzheimer's Disease Neuroimaging Initiative

The AD Neuroimaging Initiative Last fall, the NIA, a component of the National Institutes of Health (NIH), and its partners began funding the AD...

Therapeutic Exploration of Metabotropic Glutamate Receptor Antagonists in Parkinson’s Disease by Positron Emission Tomography

There is great interest in developing pharmacological compounds that function through metabotropic glutamate receptors (mGluRs) as modulators of...

Understanding Brain Anatomy in Autism – Findings from Structural Neuroimaging

Structural Magnetic Resonance Imaging The development of computed tomography (CT) in the early 1970s was a major breakthrough in clinical brain...

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