Articles
However, presently, no fully satisfying efficacy "disease-modification" study design exists, and no drug has yet been approved for that indication....
Multiple Sclerosis In multiple sclerosis (MS), 2008 has been a big year in terms of diseasemodifying therapies. Results from key clinical trials...
Parkinson’s disease (PD) is the second most common neurodegenerative disorder and affects more than one in 100 people over the age of 65.1 The...
The initiation of antiparkinsonian treatment in early Parkinson’s disease (PD) is followed by a phase of good to excellent symptomatic response in...
In recent years, a novel gel form of levodopa/carbidopa (Duodopa®) has enabled infusion through percutaneous endoscopic gastrostomy (PEG) directly...
The prevalence of Parkinson’s disease (PD) is now estimated to be approximately 1 % in individuals over 60 years of age, with 4.1–4.6 million...
"Many people have a false sense of security about these herbal products because they are seen as 'natural,'" said Arshad Jahangir, M.D.,...
Another common form of dementia is Lewy body dementia (LBD). As its name suggests, LBD is characterized by the presence of Lewy bodies—...
A slow progressive loss of dopaminergic neurons accompanies normal aging, and exposure to harmful environmental factors may cause PD by accelerating...
There is a change in the clinical manifestation of Parkinson’s disease (PD) over time. Figure 1 provides a schematic overview of this process,...
Our as-yet quite short experience with continuous levodopa infusion (Duodopa) therapy at the University of Barcelona began 18 months ago. We decided...
The Drug Delivery System The first studies of intravenous and intraduodenal infusions of levodopa utilized water solutions of levodopa. The...
However, at this time, many questions are still unanswered and many options are still debated. What is the appropriate structure to stimulate or to...
Advantages and Disadvantages of DBS DBS has many advantages over other surgical approaches to PD. It is a reversible procedure that allows the option...
However, as the disease progresses, disabling medication-related side effects, particularly motor fluctuations and dyskinesia, often occur and can...
This article provides an update on the epidemiological, clinical and pathological features of PD-D and recent treatment efforts Epidemiology...
The estimated prevalence of depression in PD varies according to the type of mood assessment applied (interview versus self-report questionnaire),...
Introduction Aripiprazole is one of the recently introduced atypical antipsychotics (AAs) used in the treatment of psychosis related to schizophrenia...
Since the primary pathological consequences of PD are due to the degeneration of a specific set of neurons that specifically release the...
Performing two tasks simultaneously (dual task performance) is a frequent activity in human life. However, performing dual tasks can be difficult....
