Articles

Breakthrough Seizures—Approach to Prevention and Diagnosis

What causes breakthrough seizures?There are a number of potential causes of the unexpected occurrence of a breakthrough seizure. One important factor...

Current Developments in Epilepsy Treatment

First Seizure and New Onset EpilepsyWhen a patient has suffered the first epileptic seizure, a decision whether to treat or not is based on the risk...

Depression in Epilepsy Mechanisms and Therapeutic Approaches

Epilepsy and Depression – A Bi-directional RelationshipAssessing the prevalence of depression from selected clinical samples of patients with...

Management of Stroke-related Seizures

Seizures can be classified as those of early and those of late onset in a paradigm comparable to post-traumatic epilepsy, with an arbitrary dividing...

Modern Approaches to Epilepsy Management

It has long been recognized that seizures will be or will become refractory to pharmacotherapy in more than 30% of patients, and that localized...

New Technique to Pinpoint Seizure Location and Improve Surgical Outcomes

Epilepsy is a disorder characterized by the occurrence of two or more seizures, and it affects more than 3 million Americans. "About 10 percent...

Nocturnal Frontal Lobe Epilepsy - An Update on Differential Diagnosis with Non-rapid Eye Movement Parasomnia

NFLE is characterised by onset during infancy or childhood with persistence in adulthood, family history of similar NFL seizures and nocturnal...

Realtime Detection, Quantification, Warning, and Control of Epileptic Seizures— The Foundations of a New Epileptology

Realtime automated seizure detection, the obligatory condition for implementation of contingent warning and therapies, has been attempted with...

Recent Advances in the Neurochemistry of Epilepsy

Epilepsy is a common neurological disorder, affecting 1–2% of the population worldwide, and is characterised by recurrent spontaneous seizures....

Seizure Semiology, Neurotransmitter Receptors and Cellular-stress Responses in Pentylenetetrazole Models of Epilepsy

Epilepsy affects about 1% of the human population at some point during their life. The causes of human epilepsies are diverse, ranging from defects...

The Need for Broad Spectrum and Safe Anti-epileptic Drugs in Childhood Epilepsy

Only in a few situations is the best choice not to start treatment. For instance, in benign rolandic epilepsy with only nightly, partial seizures...

The Role of Vagus Nerve Stimulation in the Treatment of Epilepsy

Following the first encouraging human trials in 1988, 1,2 several controlled studies have demonstrated the antiepileptic efficacy of adjunctive vagus...

The Top Five Advances in the Use of Ketogenic Diets for Epilepsy and Beyond

How has the KD changed from an unproven, ‘alternative’ epilepsy treatment to an established, non-pharmacological medical therapy over the...

Topiramate in the Treatment of Epilepsy - A Review

Mechanism of Action of Topiramate Although the exact mechanism of action of TPM remains unknown, multiple mechanisms have been hypothesised based on...

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