Articles

This two-step procedure, which relies on the Diagnostic and Statistic Manual of Mental Disorders IV Text Revision (DSM-IV-TR) and the National...

Alzheimer’s disease (AD) is the most common form of dementia, and worldwide affects 20–30 million individuals over 60 years of age. In 1907 Alois...

Currently, cholinesterase inhibitors are the mainstay in clinical practice of symptomatic treatment for Alzheimer’s disease (AD). They are believed...

Multiple Sclerosis In multiple sclerosis (MS), 2008 has been a big year in terms of diseasemodifying therapies. Results from key clinical trials...

Alzheimer’s disease (AD) is a neurodegenerative age-related progressive disease and the most common cause of dementia in the elderly.1 Current...

This delay in recognition of AD as a major neurological disease of aging does not reflect its impact.There are the personal tragedies that accompany...

Numerous clinical trials are under way to evaluate therapeutic approaches to stop the progression of Alzheimer’s disease (AD). Despite the...

Furthermore, in most studies, the role of tau has been understated for a long time. To apprehend this role, the Inserm team has developed a...

Alzheimer’s disease (AD) is a complex, heterogeneous age-related disorder and the most common form of dementia. It is characterised clinically by a...

Another common form of dementia is Lewy body dementia (LBD). As its name suggests, LBD is characterized by the presence of Lewy bodies—...

There has been remarkable progress in developing biological markers (biomarkers) that provide insight into the progression of Alzheimer’s disease...

Dementia is a term used to describe acquired cognitive impairments that interfere with day-to-day functioning. In addition to describing a clinical...

Natural History of Alzheimer’s Disease The natural history of AD can be broadly considered as comprising a pre-symptomatic stage during which...

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by extracellular deposition of pathogenic amyloid-beta (Aβ)...

Oral levodopa remains the most effective symptomatic drug for Parkinson’s disease (PD); however, its long-term use is limited by the...

The following interventions need to be considered in a patient with neurodegenerative dementia of the ‘Alzheimer type’. Symptomatic...

Parkinson’s Disease Parkinson’s disease (PD) is a slowly progressive neurodegenerative disease characterized by tremor, rigidity,...

This article provides an update on the epidemiological, clinical and pathological features of PD-D and recent treatment efforts Epidemiology...

Terminology Dementia refers to a change in intellectual function including a memory impairment, along with an additional cognitive deficit in at...

DISEASE/CONDITION(S) Alzheimer's disease (AD) GUIDELINE CATEGORY Assessment of Therapeutic Effectiveness Management Treatment CLINICAL...