Articles
Mayo Clinic Researchers Find Dementia in Diabetics Differs from Dementia in Nondiabetics
JACKSONVILLE, Fla. — Researchers from Mayo Clinic's Florida campus say that dementia in some diabetics appears to be caused often by vascular...
Mayo Clinic Researchers Find Gene That Contributes to Two Different and Common Neurological Movement Disorders
In the September issue of Parkinsonism & Related Disorders, the researchers' report that a variant in LINGO1, a gene involved in...
Mayo Clinic Researchers Show Brain Waves Can "Write" on a Computer in Early Tests
Researchers say these findings, presented at the 2009 annual meeting of the American Epilepsy Society, represent concrete progress toward a ...
Mayo Clinic Study Finds Apathy and Depression Predict Progression from Mild Cognitive Impairment to Dementia
ROCHESTER, Minn. — A new Mayo Clinic study found that apathy and depression significantly predict an individual's progression from mild cognitive...
Mayo Clinic Study Finds Earliest Evidence of Memory Decline in Middle-aged People at Genetic Risk for Alzheimer's Disease
These and other findings reported by researchers and their colleagues in the Arizona Alzheimer's Consortium support the...
Memantine in Moderate-to-severe Alzheimer's Disease
Current pharmacotherapy is focused on delaying the symptomatic progression of AD. Although the cause of the disease remains unknown, acetylcholine...
Merz Pharmaceuticals GmbH
Another focus is the clinical and aesthetic dermatology. CNS Serious neurological diseases significantly restrict patients’ everyday lives and...
Mild Cognitive Impairment - A Preclinical State of Alzheimer's Disease?
A considerable larger population suffers from a transition phase between healthy cognitive ageing and dementia for which several definitions and...
Mitochondrial Dysfunction and Oxidative Stress in Alzheimer’s Disease
Alzheimer’s disease (AD) is the most common form of dementia and affects millions of people worldwide. The disorder is characterised by...
Monoamine Oxidase Type B Inhibitors in the Treatment of Early Parkinson’s Disease
Parkinson’s disease (PD) is a progressive neurodegenerative disorder. It has been classically described as a movement disorder involving the...
New Horizons in the Treatment of Alzheimer’s Disease—Immunotherapeutics
Active Anti-amyloid Immunotherapy with AAC-001 A-beta is widely hypothesized to be the major therapeutic target in AD. Unfortunately, there has not...
Novel Biomarkers and Therapeutic Options to Address Neuronal Injury
The Significance of One-carbon Metabolism Abnormalities of one-carbon metabolism lead to elevated levels of Hcy. In one-carbon metabolism, methionine...
Olfactory Function in Parkinson’s Disease
There is convincing evidence from numerous studies using both psychophysical and electrophysiological approaches that olfaction is...
Optical Coherence Tomography –A New Monitoring Tool for Multiple Sclerosis?
Multiple sclerosis (MS) is an immune-mediated disease of the central nervous system (CNS) with inflammatory demyelinating lesions and...
Pathology of the Cleaved Tau Protein in the Context of Toxicity and the Formation of Neurofibrillary Tangles
Alzheimer’s disease (AD) is the most common type of dementia and is characterised by memory loss and cognitive impairment in the elderly. These...
Pharmacological Treatment of Alzheimer’s Disease
Although there have been tremendous developments in the understanding of the molecular biology of Alzheimer’s disease (AD), this has not yet been...
Pharmacotherapy of Alzheimer's Disease Current and Future Perspectives
Each of these stages can be targeted for specific drug treatments, requiring different trial designs and outcomes: • a healthy elderly...
Positron Emission Tomography Imaging in Dementia
Glucose is the main energy supply for the brain. Its metabolism maintains ion gradients and glutamate turnover and is closely coupled to neuronal...
Potentially Modifiable Risk Factors in the Development of Alzheimer’s Disease
As the number of people over 65 years of age continues to rise worldwide, preserving the cognitive health of older adults has become a major societal...
Prospects for Treatment of Symptomatic Alzheimer’s Disease
The cholinesterase inhibitors are clearly palliative therapies. Since the late 1970s it has been known that there is a cholinergic deficit in the...
