Practice parameter: anticonvulsant prophylaxis in patients with newly diagnosed brain tumors. Report of the Quality Standards Subcommittee of the American Academy of Neurology.

Practice parameter: anticonvulsant prophylaxis in patients with newly diagnosed brain tumors. Report of the Quality Standards Subcommittee of the American Academy of Neurology.

29 October 2008
American Academy of Neurology - Medical Specialty Society
Summary ,

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GUIDELINE OBJECTIVE(S)

To review the evidence on the administration of prophylactic anticonvulsants to patients with brain tumors and to provide specific recommendations based on the analysis of the evidence

TARGET POPULATION

Patients with newly diagnosed brain tumors (primary or metastatic)

INTERVENTIONS AND PRACTICES CONSIDERED

Prophylactic use of anticonvulsant medications (e.g., phenytoin [Dilantin], carbamazepine, phenobarbital, and valproic acid [Depakote]) in patients with primary or metastatic brain tumors.

MAJOR OUTCOMES CONSIDERED

* Seizure-free survival (time to first seizure or death, whichever occurred first)
* Overall survival

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