The Use of Magnetic Resonance Imaging-guided Focused Ultrasound in Movement Disorders—A Review

US Neurology, 2017;13(2):74–7 DOI: https://doi.org/10.17925/USN.2017.13.02.74

Abstract:

The use of surgical treatments for movement disorders has been well established for several decades, with a strong focus, in the past, on ablative lesioning procedures and, more recently, deep brain stimulation. Magnetic resonance imaging (MRI)-guided focused ultrasound (MRgFUS) is emerging as a newly recognized surgical technique for the treatment of various movement disorders. The most robust data, demonstrating safety and efficacy of MRgFUS, have been published in trials directed at treatment of essential tremor (ET); however, many trials are underway to define its role in other movement disorders, such as Parkinson’s disease with preliminary results echoing those from studies in ET. The full potential for use of MRgFUS, both in the field of movement disorders and beyond, is only beginning to be explored.
Keywords: Essential tremor, Parkinson’s disease, tremor, thalamotomy, focused ultrasound
Disclosure: Lauren S Talman and Binit B Shah have nothing to declare in relation to this article. No funding was received in the publication of this article.

Authorship: All named authors meet the International Committee of Medical Journal Editors (ICMJE) criteria for authorship of this manuscript, take responsibility for the integrity of the work as a whole, and have given final approval to the version to be published.

Received: May 19, 2017 Accepted July 06, 2017
Correspondence: Binit B Shah, MD. PO Box 800394, McKim Hall 2nd Floor, Charlottesville, VA 22908, US. E: binitshah@virginia.edu
Open Access: This article is published under the Creative Commons Attribution Noncommercial License, which permits any noncommercial use, distribution, adaptation, and reproduction provided the original author(s) and source are given appropriate credit.

Keywords: Essential tremor, Parkinson’s disease, tremor, thalamotomy, focused ultrasound