The use of etoricoxib to treat an idiopathic stabbing headache: a case report
The use of etoricoxib to treat an idiopathic stabbing headache: a case report
Abstract
According to the International Headache Society, idiopathic stabbing headache (ISH), an indomethacin-responsive headache syndrome, is a paroxysmal disorder of short duration manifested as head pain occurring as a single stab or a series of stabs involving the area supplied in the distribution of the first division of the trigeminal nerve. Stabs last for approximately a few seconds, occurring and recurring from once to multiple times per day in an irregular frequency, with no underlying attributable disorder.
Previously indomethacin was the principle treatment option for ISH, despite therapeutic failure in up to 35% of cases, until reports showed gabapentin, melatonin and selective cyclo-oxygenase-2 (COX-2) inhibitors were also possibly effective. In this report we present the full case report of an 88 year old lady with a history of untreated ISH where etoricoxib, a selective COX-2 inhibitor, was used to effectively treat her ISH.
Introduction
Idiopathic stabbing headache (ISH) was first described in 1964 by Lansche [1] and over the years in has been known by many synonyms, e.g. "ophthalmodynia periodica", "ice-pick headache syndrome" and "jabs and jolts". Recently it has been included as a separate entity in the classification of the International Headache Society (IHS) – "other primary headaches". [2]
ISH is a paroxysmal disorder manifested as transient painful stabs, predominantly or exclusively felt in the distribution of the ophthalmic division of the trigeminal nerve [3]. It has a life-time prevalence in the region of 2% [4] with onset primarily in middle or late stages of life (mean age of 47 years) [5] and a female preponderance. [5]
etoricoxib, idiopathic stabbing headache, International Headache Society, ISH, ophthalmodynia periodica,
- Lansche RK: Ophtalmodynia periodica. Headache 1964, 4:247-9.
- International Headache Society Classification Subcommittee: International classification of headache disorders. Cephalalgia 3rd edition. 2004, 24(suppl 1):1-160.
- Franca MC Jr, Costa ALC, Maciel JA Jr: Gabapentin-responsive idiopathic stabbing headache. Cephalalgia 2004, 24(11):993-6.
- Rassmussen BK: Epidemiology of headache. Cephalalgia 1995, 15:45-68.
- Dodick DW: Indomethacin-responsive headache syndromes. Curr Pain Headache Rep 2004, 8(1):19-26.
- Pareja JA, Ruiz J, Isla C, al-Sabbah H, Espejo J: Idiopathic stabbing headache (jabs and jolts syndrome). Cephalalgia 1996, 16:93-6.
- Jacome DE: head syndrome and idiopathic stabbing headache relieved by nifedipine. Cephalalgia 2001, 21:617-8.
- Rozen TD: Melatonin as a treatment for indomethacinresponsive headaches. Neurology 2003, 61(6):865-6.
- Piovesan EJ, Zukerman E, Kowacs PA, Werneck LC: COX-2 inhibitor for the treatment of idiopathic headache secondary to cerebrovascular disease. Cephalalgia 2002, 22(3):197-200.
- Raskin NH, Schwartz RK: Icepick-like pain. Neurology 1980, 30:203-5.
- Hermann M, Ruschitzka F: Cardiovascular risk of cyclooxygenase- 2 inhibitors and traditional non-steroidal anti-inflammatory drugs. Ann Med 2007, 39(1):18-27.
Specialities:
- Neurology
- ADHD
- Advanced Parkinson's Disease
- Anxiety Disorder
- Brain Cancer
- Cerebrovascular Disease
- Dementia
- Epilepsy
- Mood Disorders
- Motor/Movement Disorder
- Multiple Sclerosis
- Neuroimaging
- Neurosurgery
- Obsessive-Compulsive Disorder
- Pain/Headache
- Parkinson's Disease
- Psychiatry
- Schizophrenia
- Sleep Disorder
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- 16 February 2012
- 1 March 2012
- 1 March 2012










