Treatment resistant trigeminal neuralgia relieved with oral sumatriptan: a case report
Treatment resistant trigeminal neuralgia relieved with oral sumatriptan: a case report
Introduction: Treatment-resistant trigeminal neuralgia is a distressing condition, for both the patient and the treating doctor. To our knowledge, there are no reported cases of trigeminal neuralgia successfully treated with oral sumatriptan in the literature.
Case presentation: A 51-year-old Caucasian woman was prescribed opiate analgesia for management of her treatment-resistant trigeminal neuralgia. Given the possible harmful effects of initiating such a course of treatment, a speculative therapeutic trial with oral sumatriptan was initiated with a successful outcome.
Conclusion: This case raises the hypothesis that oral sumatriptan may be an effective drug in the treatment of trigeminal neuralgia. Further research is required to test this theory.
Introduction
One of the challenges in primary care is the ongoing management of patients with chronic painful syndromes who have not responded to the standard treatment regimens. Polypharmacy, multiple speciality referrals, patient dissatisfaction, depression, frequent consultations and physician frustration often ensues [1]. Such conditions tend to have a high morbidity and low mortality. Trigeminal neuralgia is a typical example of such a condition. We present the case of a middle-aged woman who, despite neurosurgical decompressive surgery, radiofrequency ablation therapy, as well as multiple speciality referrals including dentistry and a specialist pain clinic review, continued to experience frequent, severe and disabling episodes of right-sided facial pain, attributed to trigeminal neuralgia. Her symptoms rapidly responded to a trial of oral sumatriptan 50 mg and are currently well controlled with intermittent sumatriptan and maintenance propranolol.
This case highlights a further possible treatment option for trigeminal neuralgia resistant to standard treatment options.
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Specialities:
- Neurology
- ADHD
- Advanced Parkinson's Disease
- Anxiety Disorder
- Brain Cancer
- Cerebrovascular Disease
- Dementia
- Epilepsy
- Mood Disorders
- Motor/Movement Disorder
- Multiple Sclerosis
- Neuroimaging
- Neurosurgery
- Obsessive-Compulsive Disorder
- Pain/Headache
- Parkinson's Disease
- Psychiatry
- Schizophrenia
- Sleep Disorder
- Stroke
- 16 February 2012
- 1 March 2012
- 1 March 2012










